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The intact nephron hypothesis: the concept and its implications for phosphate management in CKD-related mineral and bone disorder
Mechanistic understanding of secondary hyperparathyroidism, vascular calcification, and regulation of phosphate metabolism in chronic kidney disease (CKD) has advanced significantly in the past five decades. In 1960, Bricker developed the ‘intact nephron hypothesis', opening the door for hundre...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260962/ https://www.ncbi.nlm.nih.gov/pubmed/21346721 http://dx.doi.org/10.1038/ki.2011.23 |