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Characterization of an Isotype-Dependent Monoclonal Antibody against Linear Neutralizing Epitope Effective for Prophylaxis of Enterovirus 71 Infection

BACKGROUND: Enterovirus 71 (EV71) is the main causative agent of Hand, Foot and Mouth disease (HFMD) and is associated with severe neurologic complications and mortalities. At present, there is no vaccine or therapeutic available for treatment. METHODOLOGY/PRINCIPAL FINDING: In this study, we genera...

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Detalles Bibliográficos
Autores principales:	Lim, Xiao Fang, Jia, Qiang, Khong, Wei Xin, Yan, Benedict, Premanand, Balraj, Alonso, Sylvie, Chow, Vincent T. K., Kwang, Jimmy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261156/ https://www.ncbi.nlm.nih.gov/pubmed/22279543 http://dx.doi.org/10.1371/journal.pone.0029751

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