Cargando…

Low-Dosage Inhibition of Dll4 Signaling Promotes Wound Healing by Inducing Functional Neo-Angiogenesis

Recent findings regarding Dll4 function in physiological and pathological conditions indicate that this Notch ligand may constitute an important therapeutic target. Dll4 appears to be a major anti-angiogenic agent, occupying a central role in various angiogenic pathways. The first trials of anti-Dll...

Descripción completa

Detalles Bibliográficos
Autores principales: Trindade, Alexandre, Djokovic, Dusan, Gigante, Joana, Badenes, Marina, Pedrosa, Ana-Rita, Fernandes, Ana-Carina, Lopes-da-Costa, Luís, Krasnoperov, Valery, Liu, Ren, Gill, Parkash S., Duarte, António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261161/
https://www.ncbi.nlm.nih.gov/pubmed/22279550
http://dx.doi.org/10.1371/journal.pone.0029863