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Low-Dosage Inhibition of Dll4 Signaling Promotes Wound Healing by Inducing Functional Neo-Angiogenesis
Recent findings regarding Dll4 function in physiological and pathological conditions indicate that this Notch ligand may constitute an important therapeutic target. Dll4 appears to be a major anti-angiogenic agent, occupying a central role in various angiogenic pathways. The first trials of anti-Dll...
Autores principales: | Trindade, Alexandre, Djokovic, Dusan, Gigante, Joana, Badenes, Marina, Pedrosa, Ana-Rita, Fernandes, Ana-Carina, Lopes-da-Costa, Luís, Krasnoperov, Valery, Liu, Ren, Gill, Parkash S., Duarte, António |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261161/ https://www.ncbi.nlm.nih.gov/pubmed/22279550 http://dx.doi.org/10.1371/journal.pone.0029863 |
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