Amyloid Precursor Protein Is Required for Normal Function of the Rod and Cone Pathways in the Mouse Retina

Amyloid precursor protein (APP) is a transmembrane glycoprotein frequently studied for its role in Alzheimer's disease. Our recent study in APP knockout (KO) mice identified an important role for APP in modulating normal neuronal development in the retina. However the role APP plays in the adul...

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Detalles Bibliográficos
Autores principales: Ho, Tracy, Vessey, Kirstan A., Cappai, Roberto, Dinet, Virginie, Mascarelli, Frédéric, Ciccotosto, Giuseppe D., Fletcher, Erica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261162/
https://www.ncbi.nlm.nih.gov/pubmed/22279552
http://dx.doi.org/10.1371/journal.pone.0029892

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