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Membrane-Bound IL-21 Promotes Sustained Ex Vivo Proliferation of Human Natural Killer Cells

NK cells have therapeutic potential for a wide variety of human malignancies. However, because NK cells expand poorly in vitro, have limited life spans in vivo, and represent a small fraction of peripheral white blood cells, obtaining sufficient cell numbers is the major obstacle for NK-cell immunot...

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Detalles Bibliográficos
Autores principales:	Denman, Cecele J., Senyukov, Vladimir V., Somanchi, Srinivas S., Phatarpekar, Prasad V., Kopp, Lisa M., Johnson, Jennifer L., Singh, Harjeet, Hurton, Lenka, Maiti, Sourindra N., Huls, M. Helen, Champlin, Richard E., Cooper, Laurence J. N., Lee, Dean A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261192/ https://www.ncbi.nlm.nih.gov/pubmed/22279576 http://dx.doi.org/10.1371/journal.pone.0030264

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