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Inhibition of HERG1 K(+) channel protein expression decreases cell proliferation of human small cell lung cancer cells

HERG (human ether-à-go-go-related gene) K(+) currents fulfill important ionic functions in cardiac and other excitable cells. In addition, HERG channels influence cell growth and migration in various types of tumor cells. The mechanisms underlying these functions are still not resolved. Here, we inv...

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Detalles Bibliográficos
Autores principales: Glassmeier, Günter, Hempel, Kathrin, Wulfsen, Iris, Bauer, Christiane K., Schumacher, Udo, Schwarz, Jürgen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261411/
https://www.ncbi.nlm.nih.gov/pubmed/22075718
http://dx.doi.org/10.1007/s00424-011-1045-z