Cargando…
Anaphylaxis Triggered by Benzyl Benzoate in a Preparation of Depot Testosterone Undecanoate
We report the first case of an anaphylactic reaction to Reandron 1000 (depot testosterone undecanoate with a castor oil and benzyl benzoate vehicle). While considered to have a favourable safety profile, serious complications such as oil embolism and anaphylaxis can occur. In our patient, skin testi...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261473/ https://www.ncbi.nlm.nih.gov/pubmed/22272209 http://dx.doi.org/10.1155/2012/384054 |
_version_ | 1782221599274958848 |
---|---|
author | Ong, Gregory S. Y. Somerville, Colin P. Jones, Timothy W. Walsh, John P. |
author_facet | Ong, Gregory S. Y. Somerville, Colin P. Jones, Timothy W. Walsh, John P. |
author_sort | Ong, Gregory S. Y. |
collection | PubMed |
description | We report the first case of an anaphylactic reaction to Reandron 1000 (depot testosterone undecanoate with a castor oil and benzyl benzoate vehicle). While considered to have a favourable safety profile, serious complications such as oil embolism and anaphylaxis can occur. In our patient, skin testing identified benzyl benzoate to be the trigger, with no reaction to castor oil or testosterone undecanoate components. As benzyl benzoate exists in multiple pharmaceuticals, foods, and cosmetics, individual components of pharmaceuticals should be tested when investigating drug allergies. Doctors should be alert to the potential for serious reactions to any of the components of Reandron 1000. |
format | Online Article Text |
id | pubmed-3261473 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-32614732012-01-23 Anaphylaxis Triggered by Benzyl Benzoate in a Preparation of Depot Testosterone Undecanoate Ong, Gregory S. Y. Somerville, Colin P. Jones, Timothy W. Walsh, John P. Case Rep Med Case Report We report the first case of an anaphylactic reaction to Reandron 1000 (depot testosterone undecanoate with a castor oil and benzyl benzoate vehicle). While considered to have a favourable safety profile, serious complications such as oil embolism and anaphylaxis can occur. In our patient, skin testing identified benzyl benzoate to be the trigger, with no reaction to castor oil or testosterone undecanoate components. As benzyl benzoate exists in multiple pharmaceuticals, foods, and cosmetics, individual components of pharmaceuticals should be tested when investigating drug allergies. Doctors should be alert to the potential for serious reactions to any of the components of Reandron 1000. Hindawi Publishing Corporation 2012 2012-01-05 /pmc/articles/PMC3261473/ /pubmed/22272209 http://dx.doi.org/10.1155/2012/384054 Text en Copyright © 2012 Gregory S. Y. Ong et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Ong, Gregory S. Y. Somerville, Colin P. Jones, Timothy W. Walsh, John P. Anaphylaxis Triggered by Benzyl Benzoate in a Preparation of Depot Testosterone Undecanoate |
title | Anaphylaxis Triggered by Benzyl Benzoate in a Preparation of Depot Testosterone Undecanoate |
title_full | Anaphylaxis Triggered by Benzyl Benzoate in a Preparation of Depot Testosterone Undecanoate |
title_fullStr | Anaphylaxis Triggered by Benzyl Benzoate in a Preparation of Depot Testosterone Undecanoate |
title_full_unstemmed | Anaphylaxis Triggered by Benzyl Benzoate in a Preparation of Depot Testosterone Undecanoate |
title_short | Anaphylaxis Triggered by Benzyl Benzoate in a Preparation of Depot Testosterone Undecanoate |
title_sort | anaphylaxis triggered by benzyl benzoate in a preparation of depot testosterone undecanoate |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261473/ https://www.ncbi.nlm.nih.gov/pubmed/22272209 http://dx.doi.org/10.1155/2012/384054 |
work_keys_str_mv | AT onggregorysy anaphylaxistriggeredbybenzylbenzoateinapreparationofdepottestosteroneundecanoate AT somervillecolinp anaphylaxistriggeredbybenzylbenzoateinapreparationofdepottestosteroneundecanoate AT jonestimothyw anaphylaxistriggeredbybenzylbenzoateinapreparationofdepottestosteroneundecanoate AT walshjohnp anaphylaxistriggeredbybenzylbenzoateinapreparationofdepottestosteroneundecanoate |