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Cucurbitacin E Induces G(2)/M Phase Arrest through STAT3/p53/p21 Signaling and Provokes Apoptosis via Fas/CD95 and Mitochondria-Dependent Pathways in Human Bladder Cancer T24 Cells

Cucurbitacin E, a tetracyclic triterpenes compound extracted from cucurbitaceous plants, has been shown to exhibit anticancer and anti-inflammatory activities. The purpose of this study was to elucidate whether cucurbitacin E promotes cell cycle arrest and induces apoptosis in T24 cells and further...

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Detalles Bibliográficos
Autores principales:	Huang, Wen-Wen, Yang, Jai-Sing, Lin, Meng-Wei, Chen, Po-Yuan, Chiou, Shang-Ming, Chueh, Fu-Shin, Lan, Yu-Hsuan, Pai, Shu-Jen, Tsuzuki, Minoru, Ho, Wai-Jane, Chung, Jing-Gung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261502/ https://www.ncbi.nlm.nih.gov/pubmed/22272214 http://dx.doi.org/10.1155/2012/952762

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