Coreceptor gene imprinting governs thymocyte lineage fate

Immature thymocytes are bipotential cells that are signalled during positive selection to become either helper- or cytotoxic-lineage T cells. By tracking expression of lineage determining transcription factors during positive selection, we now report that the Cd8 coreceptor gene locus co-opts any co...

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Detalles Bibliográficos
Autores principales: Adoro, Stanley, McCaughtry, Thomas, Erman, Batu, Alag, Amala, Van Laethem, François, Park, Jung-Hyun, Tai, Xuguang, Kimura, Motoko, Wang, Lie, Grinberg, Alex, Kubo, Masato, Bosselut, Remy, Love, Paul, Singer, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261554/
https://www.ncbi.nlm.nih.gov/pubmed/22036949
http://dx.doi.org/10.1038/emboj.2011.388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261554/
https://www.ncbi.nlm.nih.gov/pubmed/22036949
http://dx.doi.org/10.1038/emboj.2011.388

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