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Coreceptor gene imprinting governs thymocyte lineage fate
Immature thymocytes are bipotential cells that are signalled during positive selection to become either helper- or cytotoxic-lineage T cells. By tracking expression of lineage determining transcription factors during positive selection, we now report that the Cd8 coreceptor gene locus co-opts any co...
Autores principales: | Adoro, Stanley, McCaughtry, Thomas, Erman, Batu, Alag, Amala, Van Laethem, François, Park, Jung-Hyun, Tai, Xuguang, Kimura, Motoko, Wang, Lie, Grinberg, Alex, Kubo, Masato, Bosselut, Remy, Love, Paul, Singer, Alfred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261554/ https://www.ncbi.nlm.nih.gov/pubmed/22036949 http://dx.doi.org/10.1038/emboj.2011.388 |
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