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The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer

BACKGROUND: Upregulation of the proto-oncogene plasminogen activator inhibitor-1 (PAI-1) is a common hallmark of various solid tumours, but the mechanisms controlling its expression are not fully understood. METHODS: We investigate microRNAs (miRNAs) regulating PAI-1 in a panel of normal bladder uro...

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Detalles Bibliográficos
Autores principales: Villadsen, S B, Bramsen, J B, Ostenfeld, M S, Wiklund, E D, Fristrup, N, Gao, S, Hansen, T B, Jensen, T I, Borre, M, Ørntoft, T F, Dyrskjøt, L, Kjems, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261682/
https://www.ncbi.nlm.nih.gov/pubmed/22108519
http://dx.doi.org/10.1038/bjc.2011.520