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A novel strategy for the comprehensive analysis of the biomolecular composition of isolated plasma membranes

We manufactured a novel type of lipid-coated superparamagnetic nanoparticles that allow for a rapid isolation of plasma membranes (PMs), enabling high-resolution proteomic, glycomic and lipidomic analyses of the cell surface. We used this technology to characterize the effects of presenilin knockout...

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Detalles Bibliográficos
Autores principales: Thimiri Govinda Raj, Deepak B, Ghesquière, Bart, Tharkeshwar, Arun Kumar, Coen, Katrijn, Derua, Rita, Vanderschaeghe, Dieter, Rysman, Evelien, Bagadi, Murali, Baatsen, Pieter, De Strooper, Bart, Waelkens, Etienne, Borghs, Gustaaf, Callewaert, Nico, Swinnen, Johan, Gevaert, Kris, Annaert, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261717/
https://www.ncbi.nlm.nih.gov/pubmed/22027552
http://dx.doi.org/10.1038/msb.2011.74