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Design, Synthesis, and Biological Evaluation of PKD Inhibitors

Protein kinase D (PKD) belongs to a family of serine/threonine kinases that play an important role in basic cellular processes and are implicated in the pathogenesis of several diseases. Progress in our understanding of the biological functions of PKD has been limited due to the lack of a PKD-specif...

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Detalles Bibliográficos
Autores principales: George, Kara M., Frantz, Marie-Céline, Bravo-Altamirano, Karla, LaValle, Courtney R., Tandon, Manuj, Leimgruber, Stephanie, Sharlow, Elizabeth R., Lazo, John S., Wang, Q. Jane, Wipf, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261798/
https://www.ncbi.nlm.nih.gov/pubmed/22267986
http://dx.doi.org/10.3390/pharmaceutics3020186