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Design, Synthesis, and Biological Evaluation of PKD Inhibitors
Protein kinase D (PKD) belongs to a family of serine/threonine kinases that play an important role in basic cellular processes and are implicated in the pathogenesis of several diseases. Progress in our understanding of the biological functions of PKD has been limited due to the lack of a PKD-specif...
Autores principales: | George, Kara M., Frantz, Marie-Céline, Bravo-Altamirano, Karla, LaValle, Courtney R., Tandon, Manuj, Leimgruber, Stephanie, Sharlow, Elizabeth R., Lazo, John S., Wang, Q. Jane, Wipf, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261798/ https://www.ncbi.nlm.nih.gov/pubmed/22267986 http://dx.doi.org/10.3390/pharmaceutics3020186 |
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