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A systems-based mathematical modelling framework for investigating the effect of drugs on solid tumours
BACKGROUND: Elucidating the effects of drugs on solid tumours is a highly challenging multi-level problem, since this involves many complexities associated with transport and cellular response, which in turn is characterized by highly non-linear chemical signal transduction. Appropriate systems fram...
Autores principales: | Liu, Cong, Krishnan, J, Xu, Xiao Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261817/ https://www.ncbi.nlm.nih.gov/pubmed/22152406 http://dx.doi.org/10.1186/1742-4682-8-45 |
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