Synthesis, Biological Evaluation and Mechanism Studies of Deoxytylophorinine and Its Derivatives as Potential Anticancer Agents

Previous studies indicated that (+)-13a-(S)-Deoxytylophorinine (1) showed profound anti-cancer activities both in vitro and in vivo and could penetrate the blood brain barrier to distribute well in brain tissues. CNS toxicity, one of the main factors to hinder the development of phenanthroindolizidi...

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Detalles Bibliográficos
Autores principales: Lv, Haining, Ren, Jinhong, Ma, Shuanggang, Xu, Song, Qu, Jing, Liu, Zhenjia, Zhou, Qing, Chen, Xiaoguang, Yu, Shishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261902/
https://www.ncbi.nlm.nih.gov/pubmed/22276180
http://dx.doi.org/10.1371/journal.pone.0030342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261902/
https://www.ncbi.nlm.nih.gov/pubmed/22276180
http://dx.doi.org/10.1371/journal.pone.0030342

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