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Subchronic Pulmonary Pathology, Iron Overload, and Transcriptional Activity after Libby Amphibole Exposure in Rat Models of Cardiovascular Disease
Background: Surface-available iron (Fe) is proposed to contribute to asbestos-induced toxicity through the production of reactive oxygen species. Objective: Our goal was to evaluate the hypothesis that rat models of cardiovascular disease with coexistent Fe overload would be increasingly sensitive t...
Autores principales: | Shannahan, Jonathan H., Nyska, Abraham, Cesta, Mark, Schladweiler, Mette C.J., Vallant, Beena D., Ward, William O., Ghio, Andrew J., Gavett, Stephen H., Kodavanti, Urmila P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261949/ https://www.ncbi.nlm.nih.gov/pubmed/21979745 http://dx.doi.org/10.1289/ehp.1103990 |
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