Cargando…
Impaired Chromatin Remodelling at STAT1-Regulated Promoters Leads to Global Unresponsiveness of Toxoplasma gondii-Infected Macrophages to IFN-γ
Intracellular pathogens including the apicomplexan and opportunistic parasite Toxoplasma gondii profoundly modify their host cells in order to establish infection. We have shown previously that intracellular T. gondii inhibit up-regulation of regulatory and effector functions in murine macrophages (...
Autores principales: | Lang, Christine, Hildebrandt, Anke, Brand, Franziska, Opitz, Lennart, Dihazi, Hassan, Lüder, Carsten G. K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262016/ https://www.ncbi.nlm.nih.gov/pubmed/22275866 http://dx.doi.org/10.1371/journal.ppat.1002483 |
Ejemplares similares
-
Epigenetic Control of IFN-γ Host Responses During Infection With Toxoplasma gondii
por: Nast, Roswitha, et al.
Publicado: (2020) -
Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ–mediated host defenses
por: Gay, Gabrielle, et al.
Publicado: (2016) -
Long-Term Impact of Toxoplasma gondii Infection on Human Monocytes
por: Ehmen, Hauke G., et al.
Publicado: (2019) -
Involvement of a Toxoplasma gondii Chromatin Remodeling Complex Ortholog in Developmental Regulation
por: Rooney, Peggy J., et al.
Publicado: (2011) -
Toxoplasma gondii Triggers Phosphorylation and Nuclear Translocation of Dendritic Cell STAT1 while Simultaneously Blocking IFNγ-Induced STAT1 Transcriptional Activity
por: Schneider, Anne G., et al.
Publicado: (2013)