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Ser7 Phosphorylation of the CTD Recruits the RPAP2 Ser5 Phosphatase to snRNA Genes
The carboxy-terminal domain (CTD) of the large subunit of RNA polymerase II (Pol II) comprises multiple heptapeptide repeats of the consensus Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Reversible phosphorylation of Ser2, Ser5, and Ser7 during the transcription cycle mediates the sequential recruitment of t...
Autores principales: | Egloff, Sylvain, Zaborowska, Justyna, Laitem, Clélia, Kiss, Tamás, Murphy, Shona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262128/ https://www.ncbi.nlm.nih.gov/pubmed/22137580 http://dx.doi.org/10.1016/j.molcel.2011.11.006 |
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