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Age- and region-specific hepatitis B prevalence in Turkey estimated using generalized linear mixed models: a systematic review
BACKGROUND: To provide a clear picture of the current hepatitis B situation, the authors performed a systematic review to estimate the age- and region-specific prevalence of chronic hepatitis B (CHB) in Turkey. METHODS: A total of 339 studies with original data on the prevalence of hepatitis B surfa...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262158/ https://www.ncbi.nlm.nih.gov/pubmed/22151620 http://dx.doi.org/10.1186/1471-2334-11-337 |
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author | Toy, Mehlika Önder, Fatih Oguz Wörmann, Tanja Bozdayi, A Mithat Schalm, Solko W Borsboom, Gerard J van Rosmalen, Joost Richardus, Jan Hendrik Yurdaydin, Cihan |
author_facet | Toy, Mehlika Önder, Fatih Oguz Wörmann, Tanja Bozdayi, A Mithat Schalm, Solko W Borsboom, Gerard J van Rosmalen, Joost Richardus, Jan Hendrik Yurdaydin, Cihan |
author_sort | Toy, Mehlika |
collection | PubMed |
description | BACKGROUND: To provide a clear picture of the current hepatitis B situation, the authors performed a systematic review to estimate the age- and region-specific prevalence of chronic hepatitis B (CHB) in Turkey. METHODS: A total of 339 studies with original data on the prevalence of hepatitis B surface antigen (HBsAg) in Turkey and published between 1999 and 2009 were identified through a search of electronic databases, by reviewing citations, and by writing to authors. After a critical assessment, the authors included 129 studies, divided into categories: 'age-specific'; 'region-specific'; and 'specific population group'. To account for the differences among the studies, a generalized linear mixed model was used to estimate the overall prevalence across all age groups and regions. For specific population groups, the authors calculated the weighted mean prevalence. RESULTS: The estimated overall population prevalence was 4.57, 95% confidence interval (CI): 3.58, 5.76, and the estimated total number of CHB cases was about 3.3 million. The outcomes of the age-specific groups varied from 2.84, (95% CI: 2.60, 3.10) for the 0-14-yearolds to 6.36 (95% CI: 5.83, 6.90) in the 25-34-year-old group. CONCLUSION: There are large age-group and regional differences in CHB prevalence in Turkey, where CHB remains a serious health problem. |
format | Online Article Text |
id | pubmed-3262158 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-32621582012-01-20 Age- and region-specific hepatitis B prevalence in Turkey estimated using generalized linear mixed models: a systematic review Toy, Mehlika Önder, Fatih Oguz Wörmann, Tanja Bozdayi, A Mithat Schalm, Solko W Borsboom, Gerard J van Rosmalen, Joost Richardus, Jan Hendrik Yurdaydin, Cihan BMC Infect Dis Research Article BACKGROUND: To provide a clear picture of the current hepatitis B situation, the authors performed a systematic review to estimate the age- and region-specific prevalence of chronic hepatitis B (CHB) in Turkey. METHODS: A total of 339 studies with original data on the prevalence of hepatitis B surface antigen (HBsAg) in Turkey and published between 1999 and 2009 were identified through a search of electronic databases, by reviewing citations, and by writing to authors. After a critical assessment, the authors included 129 studies, divided into categories: 'age-specific'; 'region-specific'; and 'specific population group'. To account for the differences among the studies, a generalized linear mixed model was used to estimate the overall prevalence across all age groups and regions. For specific population groups, the authors calculated the weighted mean prevalence. RESULTS: The estimated overall population prevalence was 4.57, 95% confidence interval (CI): 3.58, 5.76, and the estimated total number of CHB cases was about 3.3 million. The outcomes of the age-specific groups varied from 2.84, (95% CI: 2.60, 3.10) for the 0-14-yearolds to 6.36 (95% CI: 5.83, 6.90) in the 25-34-year-old group. CONCLUSION: There are large age-group and regional differences in CHB prevalence in Turkey, where CHB remains a serious health problem. BioMed Central 2011-12-12 /pmc/articles/PMC3262158/ /pubmed/22151620 http://dx.doi.org/10.1186/1471-2334-11-337 Text en Copyright ©2011 Toy et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited |
spellingShingle | Research Article Toy, Mehlika Önder, Fatih Oguz Wörmann, Tanja Bozdayi, A Mithat Schalm, Solko W Borsboom, Gerard J van Rosmalen, Joost Richardus, Jan Hendrik Yurdaydin, Cihan Age- and region-specific hepatitis B prevalence in Turkey estimated using generalized linear mixed models: a systematic review |
title | Age- and region-specific hepatitis B prevalence in Turkey estimated using generalized linear mixed models: a systematic review |
title_full | Age- and region-specific hepatitis B prevalence in Turkey estimated using generalized linear mixed models: a systematic review |
title_fullStr | Age- and region-specific hepatitis B prevalence in Turkey estimated using generalized linear mixed models: a systematic review |
title_full_unstemmed | Age- and region-specific hepatitis B prevalence in Turkey estimated using generalized linear mixed models: a systematic review |
title_short | Age- and region-specific hepatitis B prevalence in Turkey estimated using generalized linear mixed models: a systematic review |
title_sort | age- and region-specific hepatitis b prevalence in turkey estimated using generalized linear mixed models: a systematic review |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262158/ https://www.ncbi.nlm.nih.gov/pubmed/22151620 http://dx.doi.org/10.1186/1471-2334-11-337 |
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