erbB3 recruitment of insulin receptor substrate 1 modulates insulin-like growth factor receptor signalling in oestrogen receptor-positive breast cancer cell lines

INTRODUCTION: Recently we reported that insulin receptor substrate 1 (IRS-1), classically an adaptor protein for the insulin-like growth factor type I receptor (IGF-IR), associates with the epidermal growth factor receptor in oestrogen receptor (ER)-positive (ER+) tamoxifen-resistant breast cancer c...

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Detalles Bibliográficos
Autores principales: Knowlden, Janice M, Gee, Julia MW, Barrow, Denise, Robertson, John F, Ellis, Ian O, Nicholson, Robert I, Hutcheson, Iain R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262205/
https://www.ncbi.nlm.nih.gov/pubmed/21939528
http://dx.doi.org/10.1186/bcr3018

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