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Current views on the role of Notch signaling and the pathogenesis of human leukemia
The Notch signaling pathway is highly conserved from Drosophila to humans and plays an important role in the regulation of cellular proliferation, differentiation and apoptosis. Constitutive activation of Notch signaling has been shown to result in excessive cellular proliferation and a wide range o...
Autores principales: | Pancewicz, Joanna, Nicot, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262490/ https://www.ncbi.nlm.nih.gov/pubmed/22128846 http://dx.doi.org/10.1186/1471-2407-11-502 |
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