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Recent Clinical and Experimental Advances in Atrial Fibrillation

Atrial fibrillation (AF) is the most common arrhythmia in clinical settings (Fuster et al., 2001), and it is often associated with congestive heart diseases (Issac et al., 2007). Many studies in both laboratory and clinical settings have sought to analyze the mechanisms of AF, develop treatments bas...

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Detalles Bibliográficos
Autores principales: Miyagawa, Shigeru, Sakaguchi, Taichi, Nishi, Hiroyuki, Yoshikawa, Yasushi, Fukushima, Satsuki, Saito, Shunsuke, Sawa, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262506/
https://www.ncbi.nlm.nih.gov/pubmed/22347664
http://dx.doi.org/10.5402/2011/958189
Descripción
Sumario:Atrial fibrillation (AF) is the most common arrhythmia in clinical settings (Fuster et al., 2001), and it is often associated with congestive heart diseases (Issac et al., 2007). Many studies in both laboratory and clinical settings have sought to analyze the mechanisms of AF, develop treatments based on these mechanisms, and examine atrial remodeling in chronic AF. The aim of this paper is to analyze recent findings regarding the atrial remodeling that occurs in AF. In particular, we will describe the electrical and structural changes that involve atrial myocytes and the extracellular matrix. We will also describe the general classification and basic pathophysiology of AF and its surgical treatments.