Sterile Abscess in the Myocardium after Direct Intramyocardial Injection Related to Gene Therapy in a Swine Model

Cardiac gene therapy is one of the most promising approaches to cure patients with cardiac dysfunctions. Many ways of efficient gene transfer using viral vectors are tested, and some of them are already used in clinical settings. However, it is always important to be keenly alert to the possible com...

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Detalles Bibliográficos
Autores principales: Ishikawa, Kiyotake, Ladage, Dennis, Tilemann, Lisa, Kawase, Yoshiaki, Hajjar, Roger J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262519/
https://www.ncbi.nlm.nih.gov/pubmed/22347637
http://dx.doi.org/10.5402/2011/319453
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author Ishikawa, Kiyotake
Ladage, Dennis
Tilemann, Lisa
Kawase, Yoshiaki
Hajjar, Roger J.
author_facet Ishikawa, Kiyotake
Ladage, Dennis
Tilemann, Lisa
Kawase, Yoshiaki
Hajjar, Roger J.
author_sort Ishikawa, Kiyotake
collection PubMed
description Cardiac gene therapy is one of the most promising approaches to cure patients with cardiac dysfunctions. Many ways of efficient gene transfer using viral vectors are tested, and some of them are already used in clinical settings. However, it is always important to be keenly alert to the possible complications when a new therapy is introduced. We present a case of myocardial sterile abscess in a swine model associated with a direct myocardial injection.
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spelling pubmed-32625192012-02-16 Sterile Abscess in the Myocardium after Direct Intramyocardial Injection Related to Gene Therapy in a Swine Model Ishikawa, Kiyotake Ladage, Dennis Tilemann, Lisa Kawase, Yoshiaki Hajjar, Roger J. ISRN Cardiol Case Report Cardiac gene therapy is one of the most promising approaches to cure patients with cardiac dysfunctions. Many ways of efficient gene transfer using viral vectors are tested, and some of them are already used in clinical settings. However, it is always important to be keenly alert to the possible complications when a new therapy is introduced. We present a case of myocardial sterile abscess in a swine model associated with a direct myocardial injection. International Scholarly Research Network 2011 2011-04-06 /pmc/articles/PMC3262519/ /pubmed/22347637 http://dx.doi.org/10.5402/2011/319453 Text en Copyright © 2011 Kiyotake Ishikawa et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ishikawa, Kiyotake
Ladage, Dennis
Tilemann, Lisa
Kawase, Yoshiaki
Hajjar, Roger J.
Sterile Abscess in the Myocardium after Direct Intramyocardial Injection Related to Gene Therapy in a Swine Model
title Sterile Abscess in the Myocardium after Direct Intramyocardial Injection Related to Gene Therapy in a Swine Model
title_full Sterile Abscess in the Myocardium after Direct Intramyocardial Injection Related to Gene Therapy in a Swine Model
title_fullStr Sterile Abscess in the Myocardium after Direct Intramyocardial Injection Related to Gene Therapy in a Swine Model
title_full_unstemmed Sterile Abscess in the Myocardium after Direct Intramyocardial Injection Related to Gene Therapy in a Swine Model
title_short Sterile Abscess in the Myocardium after Direct Intramyocardial Injection Related to Gene Therapy in a Swine Model
title_sort sterile abscess in the myocardium after direct intramyocardial injection related to gene therapy in a swine model
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262519/
https://www.ncbi.nlm.nih.gov/pubmed/22347637
http://dx.doi.org/10.5402/2011/319453
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