Diffuse Involvement of Aorta in Patient with Familial Hyperlipidemia

Familial hyperlipidemia (FH) is an inherited metabolic disorder caused by low-density lipoprotein (LDL) receptor abnormality. The delayed clearance of serum LDL results in severe hypercholesterolemia, which leads to the accumulation of LDL-derived cholesterol in skin, tendons, and arterial walls.In...

Descripción completa

Detalles Bibliográficos
Autores principales: Can, Mehmet Mustafa, Tanboga, Ibrahim Halil, Akgun, Taylan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262527/
https://www.ncbi.nlm.nih.gov/pubmed/22347657
http://dx.doi.org/10.5402/2011/804767
Descripción
Sumario:Familial hyperlipidemia (FH) is an inherited metabolic disorder caused by low-density lipoprotein (LDL) receptor abnormality. The delayed clearance of serum LDL results in severe hypercholesterolemia, which leads to the accumulation of LDL-derived cholesterol in skin, tendons, and arterial walls.In homozygous form of the disease, severely atheromatous involvement of the aorta extending to the coronary ostia is almost always present, and particular surgical strategy is required to prevent atheroembolic events.

Ejemplares similares