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Electric Field Analysis of Breast Tumor Cells

An attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is important for effective treatment of tissues. This paper de...

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Detalles Bibliográficos
Autores principales: Sree, V. Gowri, Udayakumar, K., Sundararajan, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262562/
https://www.ncbi.nlm.nih.gov/pubmed/22295214
http://dx.doi.org/10.4061/2011/235926
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author Sree, V. Gowri
Udayakumar, K.
Sundararajan, R.
author_facet Sree, V. Gowri
Udayakumar, K.
Sundararajan, R.
author_sort Sree, V. Gowri
collection PubMed
description An attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is important for effective treatment of tissues. This paper deals with the electric field distribution study of a tissue model using MAXWELL 3D Simulator. Our results indicate that tumor tissue had lower electric field strength compared to normal cells, which makes them susceptible to electrical-pulse-mediated drug delivery. This difference could be due to the altered properties of tumor cells compared to normal cells, and our results corroborate this.
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spelling pubmed-32625622012-01-31 Electric Field Analysis of Breast Tumor Cells Sree, V. Gowri Udayakumar, K. Sundararajan, R. Int J Breast Cancer Research Article An attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is important for effective treatment of tissues. This paper deals with the electric field distribution study of a tissue model using MAXWELL 3D Simulator. Our results indicate that tumor tissue had lower electric field strength compared to normal cells, which makes them susceptible to electrical-pulse-mediated drug delivery. This difference could be due to the altered properties of tumor cells compared to normal cells, and our results corroborate this. SAGE-Hindawi Access to Research 2011 2011-12-01 /pmc/articles/PMC3262562/ /pubmed/22295214 http://dx.doi.org/10.4061/2011/235926 Text en Copyright © 2011 V. Gowri Sree et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sree, V. Gowri
Udayakumar, K.
Sundararajan, R.
Electric Field Analysis of Breast Tumor Cells
title Electric Field Analysis of Breast Tumor Cells
title_full Electric Field Analysis of Breast Tumor Cells
title_fullStr Electric Field Analysis of Breast Tumor Cells
title_full_unstemmed Electric Field Analysis of Breast Tumor Cells
title_short Electric Field Analysis of Breast Tumor Cells
title_sort electric field analysis of breast tumor cells
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262562/
https://www.ncbi.nlm.nih.gov/pubmed/22295214
http://dx.doi.org/10.4061/2011/235926
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