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Electric Field Analysis of Breast Tumor Cells
An attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is important for effective treatment of tissues. This paper de...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262562/ https://www.ncbi.nlm.nih.gov/pubmed/22295214 http://dx.doi.org/10.4061/2011/235926 |
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author | Sree, V. Gowri Udayakumar, K. Sundararajan, R. |
author_facet | Sree, V. Gowri Udayakumar, K. Sundararajan, R. |
author_sort | Sree, V. Gowri |
collection | PubMed |
description | An attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is important for effective treatment of tissues. This paper deals with the electric field distribution study of a tissue model using MAXWELL 3D Simulator. Our results indicate that tumor tissue had lower electric field strength compared to normal cells, which makes them susceptible to electrical-pulse-mediated drug delivery. This difference could be due to the altered properties of tumor cells compared to normal cells, and our results corroborate this. |
format | Online Article Text |
id | pubmed-3262562 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | SAGE-Hindawi Access to Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-32625622012-01-31 Electric Field Analysis of Breast Tumor Cells Sree, V. Gowri Udayakumar, K. Sundararajan, R. Int J Breast Cancer Research Article An attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is important for effective treatment of tissues. This paper deals with the electric field distribution study of a tissue model using MAXWELL 3D Simulator. Our results indicate that tumor tissue had lower electric field strength compared to normal cells, which makes them susceptible to electrical-pulse-mediated drug delivery. This difference could be due to the altered properties of tumor cells compared to normal cells, and our results corroborate this. SAGE-Hindawi Access to Research 2011 2011-12-01 /pmc/articles/PMC3262562/ /pubmed/22295214 http://dx.doi.org/10.4061/2011/235926 Text en Copyright © 2011 V. Gowri Sree et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Sree, V. Gowri Udayakumar, K. Sundararajan, R. Electric Field Analysis of Breast Tumor Cells |
title | Electric Field Analysis of Breast Tumor Cells |
title_full | Electric Field Analysis of Breast Tumor Cells |
title_fullStr | Electric Field Analysis of Breast Tumor Cells |
title_full_unstemmed | Electric Field Analysis of Breast Tumor Cells |
title_short | Electric Field Analysis of Breast Tumor Cells |
title_sort | electric field analysis of breast tumor cells |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262562/ https://www.ncbi.nlm.nih.gov/pubmed/22295214 http://dx.doi.org/10.4061/2011/235926 |
work_keys_str_mv | AT sreevgowri electricfieldanalysisofbreasttumorcells AT udayakumark electricfieldanalysisofbreasttumorcells AT sundararajanr electricfieldanalysisofbreasttumorcells |