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A Role for Estrogen Receptor Phosphorylation in the Resistance to Tamoxifen

About two thirds of all human breast cancer cases are estrogen receptor positive. The drug of first choice for these patients is tamoxifen. However, about half of the recurrences after removal of the primary tumor are or become resistant to this drug. While many mechanisms have been identified for t...

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Detalles Bibliográficos
Autores principales: de Leeuw, Renée, Neefjes, Jacques, Michalides, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262574/
https://www.ncbi.nlm.nih.gov/pubmed/22295213
http://dx.doi.org/10.4061/2011/232435