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A Role for Estrogen Receptor Phosphorylation in the Resistance to Tamoxifen
About two thirds of all human breast cancer cases are estrogen receptor positive. The drug of first choice for these patients is tamoxifen. However, about half of the recurrences after removal of the primary tumor are or become resistant to this drug. While many mechanisms have been identified for t...
Autores principales: | de Leeuw, Renée, Neefjes, Jacques, Michalides, Rob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262574/ https://www.ncbi.nlm.nih.gov/pubmed/22295213 http://dx.doi.org/10.4061/2011/232435 |
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