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Investigating the role of c-Jun N-terminal kinases in the proliferation of Werner syndrome fibroblasts using diaminopyridine inhibitors

Fibroblasts derived from the progeroid Werner syndrome show reduced replicative lifespan and a "stressed" morphology, both alleviated using the MAP kinase inhibitor SB203580. However, interpretation of these data is problematical because although SB203580 has the stress-activated kinases p...

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Detalles Bibliográficos
Autores principales:	Davis, Terence, Dix, Matthew C, Rokicki, Michal J, Brook, Amy JC, Widdowson, Caroline S, Kipling, David, Bagley, Mark C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Preliminary Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262757/ https://www.ncbi.nlm.nih.gov/pubmed/22152108 http://dx.doi.org/10.1186/1752-153X-5-83

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