In vivo Expansion of Naïve CD4(+)CD25(high) FOXP3(+) Regulatory T Cells in Patients with Colorectal Carcinoma after IL-2 Administration

Regulatory T cells (T(reg) cells) are increased in context of malignancies and their expansion can be correlated with higher disease burden and decreased survival. Initially, interleukin 2 (IL-2) has been used as T-cell growth factor in clinical vaccination trials. In murine models, however, a role...

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Detalles Bibliográficos
Autores principales: Beyer, Marc, Schumak, Beatrix, Weihrauch, Martin R., Andres, Bettina, Giese, Thomas, Endl, Elmar, Knolle, Percy A., Classen, Sabine, Limmer, Andreas, Schultze, Joachim L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262821/
https://www.ncbi.nlm.nih.gov/pubmed/22276195
http://dx.doi.org/10.1371/journal.pone.0030422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262821/
https://www.ncbi.nlm.nih.gov/pubmed/22276195
http://dx.doi.org/10.1371/journal.pone.0030422

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