Over-Expression of Leptin Receptors in Hypothalamic POMC Neurons Increases Susceptibility to Diet-Induced Obesity

Diet-induced obesity (DIO) in rodents is characterized by impaired activation of signal-transducer and activator of transcription 3 (STAT3) by leptin receptors (LepRb) within the hypothalamic arcuate nucleus. This signaling defect likely plays an important role in development of DIO. However, the ne...

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Detalles Bibliográficos
Autores principales: Gamber, Kevin M., Huo, Lihong, Ha, Sangdeuk, Hairston, Joyce E., Greeley, Sarah, Bjørbæk, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262822/
https://www.ncbi.nlm.nih.gov/pubmed/22276206
http://dx.doi.org/10.1371/journal.pone.0030485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262822/
https://www.ncbi.nlm.nih.gov/pubmed/22276206
http://dx.doi.org/10.1371/journal.pone.0030485

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