Cargando…
Over-Expression of Leptin Receptors in Hypothalamic POMC Neurons Increases Susceptibility to Diet-Induced Obesity
Diet-induced obesity (DIO) in rodents is characterized by impaired activation of signal-transducer and activator of transcription 3 (STAT3) by leptin receptors (LepRb) within the hypothalamic arcuate nucleus. This signaling defect likely plays an important role in development of DIO. However, the ne...
Autores principales: | Gamber, Kevin M., Huo, Lihong, Ha, Sangdeuk, Hairston, Joyce E., Greeley, Sarah, Bjørbæk, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262822/ https://www.ncbi.nlm.nih.gov/pubmed/22276206 http://dx.doi.org/10.1371/journal.pone.0030485 |
Ejemplares similares
-
Somato-Dendritic Localization and Signaling by Leptin Receptors in Hypothalamic POMC and AgRP Neurons
por: Ha, Sangdeuk, et al.
Publicado: (2013) -
Correction: Somato-Dendritic Localization and Signaling by Leptin Receptors in Hypothalamic POMC and AgRP Neurons
por: Ha, Sangdeuk, et al.
Publicado: (2013) -
Magel2 knockdown in hypothalamic POMC neurons innervating the medial amygdala reduces susceptibility to diet-induced obesity
por: Choi, Yuna, et al.
Publicado: (2022) -
Proanthocyanidins potentiate hypothalamic leptin/STAT3 signalling and Pomc gene expression in rats with diet-induced obesity
por: Ibars, M, et al.
Publicado: (2017) -
Magel2 Is Required for Leptin-Mediated Depolarization of POMC Neurons in the Hypothalamic Arcuate Nucleus in Mice
por: Mercer, Rebecca E., et al.
Publicado: (2013)