Rac1 Regulates the NLRP3 Inflammasome Which Mediates IL-1beta Production in Chlamydophila pneumoniae Infected Human Mononuclear Cells

Chlamydophila pneumoniae causes acute respiratory tract infections and has been associated with development of asthma and atherosclerosis. The production of IL-1β, a key mediator of acute and chronic inflammation, is regulated on a transcriptional level and additionally on a posttranslational level...

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Detalles Bibliográficos
Autores principales: Eitel, Julia, Meixenberger, Karolin, van Laak, Claudia, Orlovski, Christine, Hocke, Andreas, Schmeck, Bernd, Hippenstiel, Stefan, N'Guessan, Philippe Dje, Suttorp, Norbert, Opitz, Bastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262829/
https://www.ncbi.nlm.nih.gov/pubmed/22276187
http://dx.doi.org/10.1371/journal.pone.0030379

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