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PDGF Upregulates Mcl-1 Through Activation of β-Catenin and HIF-1α-Dependent Signaling in Human Prostate Cancer Cells
BACKGROUND: Aberrant platelet derived growth factor (PDGF) signaling has been associated with prostate cancer (PCa) progression. However, its role in the regulation of PCa cell growth and survival has not been well characterized. METHODOLOGY/PRINCIPAL FINDINGS: Using experimental models that closely...
Autores principales: | Iqbal, Shareen, Zhang, Shumin, Driss, Adel, Liu, Zhi-Ren, Kim, Hyeong-Reh Choi, Wang, Yanru, Ritenour, Chad, Zhau, Haiyen E., Kucuk, Omer, Chung, Leland W. K., Wu, Daqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262835/ https://www.ncbi.nlm.nih.gov/pubmed/22276222 http://dx.doi.org/10.1371/journal.pone.0030764 |
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