The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting macrophage emigration from plaques

Atherosclerotic plaque formation is fueled by the persistence of lipid-laden macrophages in the artery wall. The mechanisms by which these cells become trapped, thereby establishing chronic inflammation, remain unknown. Netrin-1, a neuroimmune guidance cue, was secreted by macrophages in human and m...

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Detalles Bibliográficos
Autores principales: van Gils, Janine M, Derby, Merran C, Fernandes, Luciana R, Ramkhelawon, Bhama, Ray, Tathagat D, Rayner, Katey J, Parathath, Sajesh, Distel, Emilie, Feig, Jessica L, Alvarez-Leite, Jacqueline I, Rayner, Alistair J, McDonald, Thomas O, O’Brien, Kevin D, Stuart, Lynda M, Fisher, Edward A, Lacy-Hulbert, Adam, Moore, Kathryn J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262880/
https://www.ncbi.nlm.nih.gov/pubmed/22231519
http://dx.doi.org/10.1038/ni.2205

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