B–helper neutrophils stimulate immunoglobulin diversification and production in the marginal zone of the spleen

Neutrophils utilize immunoglobulins (Igs) to clear antigen, but their role in Ig production is unknown. Here we identified neutrophils around the marginal zone (MZ) of the spleen, a B cell area specialized in T-independent Ig responses to circulating antigen. Neutrophils colonized peri-MZ areas afte...

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Detalles Bibliográficos
Autores principales: Puga, Irene, Cols, Montserrat, Barra, Carolina M., He, Bing, Cassis, Linda, Gentile, Maurizio, Comerma, Laura, Chorny, Alejo, Shan, Meimei, Xu, Weifeng, Magri, Giuliana, Knowles, Daniel M., Tam, Wayne, Chiu, April, Bussel, James B, Serrano, Sergi, Lorente, José Antonio, Bellosillo, Beatriz, Lloreta, Josep, Juanpere, Nuria, Alameda, Francesc, Baró, Teresa, de Heredia, Cristina Díaz, Torán, Núria, Català, Albert, Torrebadell, Montserrat, Fortuny, Claudia, Cusi, Victoria, Carreras, Carmen, Diaz, George A., Blander, J. Magarian, Farber, Claire-Michèle, Silvestri, Guido, Cunningham-Rundles, Charlotte, Calvillo, Michaela, Dufour, Carlo, Notarangelo, Lucia Dora, Lougaris, Vassilios, Plebani, Alessandro, Casanova, Jean-Laurent, Ganal, Stephanie C., Diefenbach, Andreas, Aróstegui, Juan Ignacio, Juan, Manel, Yagüe, Jordi, Mahlaoui, Nizar, Donadieu, Jean, Chen, Kang, Cerutti, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262910/
https://www.ncbi.nlm.nih.gov/pubmed/22197976
http://dx.doi.org/10.1038/ni.2194

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