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Meningioma interdigitated with primary central nervous system B-cell lymphoma: A case report and literature review

BACKGROUND: Simultaneous presentation of multiple primary central nervous system (CNS) malignancies is extremely rare. There have been only eight cases of meningiomas co-existing with primary cerebral lymphoma, reported in the literature. CASE DESCRIPTION: We present a case of a patient who underwen...

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Detalles Bibliográficos
Autores principales: Gordon, Amber S., Fallon, Kenneth E., Riley, Kristen O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263006/
https://www.ncbi.nlm.nih.gov/pubmed/22276235
http://dx.doi.org/10.4103/2152-7806.90716
Descripción
Sumario:BACKGROUND: Simultaneous presentation of multiple primary central nervous system (CNS) malignancies is extremely rare. There have been only eight cases of meningiomas co-existing with primary cerebral lymphoma, reported in the literature. CASE DESCRIPTION: We present a case of a patient who underwent surgical resection of an olfactory grove meningioma that was interdigitated with a primary CNS B-cell lymphoma. Following surgery, the patient was treated with high-dose methotrexate, and has no evidence of recurrence after 18 months. CONCLUSION: Because of the early recognition of these two distinct pathologies, the patient received directed adjuvant therapies, and has exceeded the survival of all other cases reported in the literature.