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A block in lineage differentiation of immortal human mammary stem / progenitor cells by ectopically-expressed oncogenes
INTRODUCTION: Emerging evidence suggests a direct role of cancer stem cells (CSCs) in the development of breast cancer. In vitro cellular models that recapitulate properties of CSCs are therefore highly desirable. We have previously shown that normal human mammary epithelial cells (hMECs) immortaliz...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263028/ https://www.ncbi.nlm.nih.gov/pubmed/22279424 http://dx.doi.org/10.4103/1477-3163.91415 |