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A block in lineage differentiation of immortal human mammary stem / progenitor cells by ectopically-expressed oncogenes

INTRODUCTION: Emerging evidence suggests a direct role of cancer stem cells (CSCs) in the development of breast cancer. In vitro cellular models that recapitulate properties of CSCs are therefore highly desirable. We have previously shown that normal human mammary epithelial cells (hMECs) immortaliz...

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Detalles Bibliográficos
Autores principales: Zhao, Xiangshan, Malhotra, Gautam K., Band, Hamid, Band, Vimla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263028/
https://www.ncbi.nlm.nih.gov/pubmed/22279424
http://dx.doi.org/10.4103/1477-3163.91415