ANCA-associated Goodpasture's syndrome in a patient with rheumatoid arthritis on penicillamine

Although penicillamine has been used effectively in the management of a variety of diseases, several adverse reactions have been observed with prolonged administration of this agent. We report a case of Goodpasture's syndrome, as a result of induction of anti-myeloperoxidase antineutrophil cyto...

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Detalles Bibliográficos
Autores principales: Sharma, R., Jain, S., Kher, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263063/
https://www.ncbi.nlm.nih.gov/pubmed/22279343
http://dx.doi.org/10.4103/0971-4065.83743
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author Sharma, R.
Jain, S.
Kher, V.
author_facet Sharma, R.
Jain, S.
Kher, V.
author_sort Sharma, R.
collection PubMed
description Although penicillamine has been used effectively in the management of a variety of diseases, several adverse reactions have been observed with prolonged administration of this agent. We report a case of Goodpasture's syndrome, as a result of induction of anti-myeloperoxidase antineutrophil cytoplasmic antibodies in a 51 year old man who was being treated with this drug for rheumatoid arthritis. This pulmonary-renal syndrome has been described on rare occasions in patients receiving penicillamine. Treatment with steroids and cyclophosphamide resulted in pulmonary and renal functional recovery.
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spelling pubmed-32630632012-01-25 ANCA-associated Goodpasture's syndrome in a patient with rheumatoid arthritis on penicillamine Sharma, R. Jain, S. Kher, V. Indian J Nephrol Case Report Although penicillamine has been used effectively in the management of a variety of diseases, several adverse reactions have been observed with prolonged administration of this agent. We report a case of Goodpasture's syndrome, as a result of induction of anti-myeloperoxidase antineutrophil cytoplasmic antibodies in a 51 year old man who was being treated with this drug for rheumatoid arthritis. This pulmonary-renal syndrome has been described on rare occasions in patients receiving penicillamine. Treatment with steroids and cyclophosphamide resulted in pulmonary and renal functional recovery. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3263063/ /pubmed/22279343 http://dx.doi.org/10.4103/0971-4065.83743 Text en Copyright: © Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sharma, R.
Jain, S.
Kher, V.
ANCA-associated Goodpasture's syndrome in a patient with rheumatoid arthritis on penicillamine
title ANCA-associated Goodpasture's syndrome in a patient with rheumatoid arthritis on penicillamine
title_full ANCA-associated Goodpasture's syndrome in a patient with rheumatoid arthritis on penicillamine
title_fullStr ANCA-associated Goodpasture's syndrome in a patient with rheumatoid arthritis on penicillamine
title_full_unstemmed ANCA-associated Goodpasture's syndrome in a patient with rheumatoid arthritis on penicillamine
title_short ANCA-associated Goodpasture's syndrome in a patient with rheumatoid arthritis on penicillamine
title_sort anca-associated goodpasture's syndrome in a patient with rheumatoid arthritis on penicillamine
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263063/
https://www.ncbi.nlm.nih.gov/pubmed/22279343
http://dx.doi.org/10.4103/0971-4065.83743
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AT kherv ancaassociatedgoodpasturessyndromeinapatientwithrheumatoidarthritisonpenicillamine

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