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Palliation of dysphagia with radiotherapy for exophytic base tongue metastases in a case of renal cell carcinoma

Base tongue involvement is a rare presentation of lingual metastases from renal cell carcinoma. A 48-year-old gentleman was treated with open radical nephrectomy and adjuvant radiotherapy for Stage II Furhman grade I clear cell carcinoma of the left kidney at an outside hospital. He presented metach...

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Autores principales: Wadasadawala, Tabassum, Kumar, Prabhash, Agarwal, Jaiprakash, Ghosh-Laskar, Sarbani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263231/
https://www.ncbi.nlm.nih.gov/pubmed/22279329
http://dx.doi.org/10.4103/0970-1591.91452
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author Wadasadawala, Tabassum
Kumar, Prabhash
Agarwal, Jaiprakash
Ghosh-Laskar, Sarbani
author_facet Wadasadawala, Tabassum
Kumar, Prabhash
Agarwal, Jaiprakash
Ghosh-Laskar, Sarbani
author_sort Wadasadawala, Tabassum
collection PubMed
description Base tongue involvement is a rare presentation of lingual metastases from renal cell carcinoma. A 48-year-old gentleman was treated with open radical nephrectomy and adjuvant radiotherapy for Stage II Furhman grade I clear cell carcinoma of the left kidney at an outside hospital. He presented metachronously 5 years later with progressive dysphagia and change of voice. Clinicoradiological evaluation revealed a large exophytic mass in the oropharynx with epicenter in the right base of tongue. Metastatic workup revealed widespread dissemination to multiple organs and bone. In view of predominant symptom of dysphagia, base tongue metastasis was treated with protracted course of palliative radiotherapy to a dose of 50 Gy in conventional fractionation over 5 weeks. This resulted in excellent and durable response at the base tongue lesion (till the time of last follow-up). Radiation therapy is an acceptable palliative strategy for advanced lingual metastasis as it produces prompt relief of pain, bleeding, and dysphagia.
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spelling pubmed-32632312012-01-25 Palliation of dysphagia with radiotherapy for exophytic base tongue metastases in a case of renal cell carcinoma Wadasadawala, Tabassum Kumar, Prabhash Agarwal, Jaiprakash Ghosh-Laskar, Sarbani Indian J Urol Case Report Base tongue involvement is a rare presentation of lingual metastases from renal cell carcinoma. A 48-year-old gentleman was treated with open radical nephrectomy and adjuvant radiotherapy for Stage II Furhman grade I clear cell carcinoma of the left kidney at an outside hospital. He presented metachronously 5 years later with progressive dysphagia and change of voice. Clinicoradiological evaluation revealed a large exophytic mass in the oropharynx with epicenter in the right base of tongue. Metastatic workup revealed widespread dissemination to multiple organs and bone. In view of predominant symptom of dysphagia, base tongue metastasis was treated with protracted course of palliative radiotherapy to a dose of 50 Gy in conventional fractionation over 5 weeks. This resulted in excellent and durable response at the base tongue lesion (till the time of last follow-up). Radiation therapy is an acceptable palliative strategy for advanced lingual metastasis as it produces prompt relief of pain, bleeding, and dysphagia. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3263231/ /pubmed/22279329 http://dx.doi.org/10.4103/0970-1591.91452 Text en Copyright: © Indian Journal of Urology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Wadasadawala, Tabassum
Kumar, Prabhash
Agarwal, Jaiprakash
Ghosh-Laskar, Sarbani
Palliation of dysphagia with radiotherapy for exophytic base tongue metastases in a case of renal cell carcinoma
title Palliation of dysphagia with radiotherapy for exophytic base tongue metastases in a case of renal cell carcinoma
title_full Palliation of dysphagia with radiotherapy for exophytic base tongue metastases in a case of renal cell carcinoma
title_fullStr Palliation of dysphagia with radiotherapy for exophytic base tongue metastases in a case of renal cell carcinoma
title_full_unstemmed Palliation of dysphagia with radiotherapy for exophytic base tongue metastases in a case of renal cell carcinoma
title_short Palliation of dysphagia with radiotherapy for exophytic base tongue metastases in a case of renal cell carcinoma
title_sort palliation of dysphagia with radiotherapy for exophytic base tongue metastases in a case of renal cell carcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263231/
https://www.ncbi.nlm.nih.gov/pubmed/22279329
http://dx.doi.org/10.4103/0970-1591.91452
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