Improved drug loading and antibacterial activity of minocycline-loaded PLGA nanoparticles prepared by solid/oil/water ion pairing method

BACKGROUND: Low drug entrapment efficiency of hydrophilic drugs into poly(lactic-co-glycolic acid) (PLGA) nanoparticles is a major drawback. The objective of this work was to investigate different methods of producing PLGA nanoparticles containing minocycline, a drug suitable for periodontal infecti...

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Detalles Bibliográficos
Autores principales: Kashi, Tahereh Sadat Jafarzadeh, Eskandarion, Solmaz, Esfandyari-Manesh, Mehdi, Marashi, Seyyed Mahmoud Amin, Samadi, Nasrin, Fatemi, Seyyed Mostafa, Atyabi, Fatemeh, Eshraghi, Saeed, Dinarvand, Rassoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263414/
https://www.ncbi.nlm.nih.gov/pubmed/22275837
http://dx.doi.org/10.2147/IJN.S27709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263414/
https://www.ncbi.nlm.nih.gov/pubmed/22275837
http://dx.doi.org/10.2147/IJN.S27709

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