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Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques
Cervical spondylotic myelopathy is a degenerative spinal disease which may lead to significant clinical morbidity. The onset of symptoms is usually insidious, with long periods of fixed disability and episodic worsening events. Regarding the pathophysiology of CSM, the repeated injuries to the spina...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scholarly Research Network
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263543/ https://www.ncbi.nlm.nih.gov/pubmed/22389818 http://dx.doi.org/10.5402/2011/463729 |
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author | Mattei, Tobias A. Goulart, Carlos R. Milano, Jeronimo B. Dutra, Luis Paulo F. Fasset, Daniel R. |
author_facet | Mattei, Tobias A. Goulart, Carlos R. Milano, Jeronimo B. Dutra, Luis Paulo F. Fasset, Daniel R. |
author_sort | Mattei, Tobias A. |
collection | PubMed |
description | Cervical spondylotic myelopathy is a degenerative spinal disease which may lead to significant clinical morbidity. The onset of symptoms is usually insidious, with long periods of fixed disability and episodic worsening events. Regarding the pathophysiology of CSM, the repeated injuries to the spinal cord are caused by both static and dynamic mechanical factors. The combination of these factors affects the spinal cord basically through both direct trauma and ischemia. Regarding the diagnosis, both static and dynamics X-rays, as well as magnetic resonance imaging are important for preoperative evaluation as well as individualizing surgical planning. The choice of the most appropriate technique is affected by patient's clinical condition radiologic findings, as well as surgeon's experience. In opposition to the old belief that patients presenting mild myelopathy should be treated conservatively, there has progressively been amount of evidence indicating that the clinical course of this disease is progressive deterioration and that early surgical intervention improves long-term functional recovery and neurological prognosis. |
format | Online Article Text |
id | pubmed-3263543 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | International Scholarly Research Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-32635432012-03-02 Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques Mattei, Tobias A. Goulart, Carlos R. Milano, Jeronimo B. Dutra, Luis Paulo F. Fasset, Daniel R. ISRN Neurol Review Article Cervical spondylotic myelopathy is a degenerative spinal disease which may lead to significant clinical morbidity. The onset of symptoms is usually insidious, with long periods of fixed disability and episodic worsening events. Regarding the pathophysiology of CSM, the repeated injuries to the spinal cord are caused by both static and dynamic mechanical factors. The combination of these factors affects the spinal cord basically through both direct trauma and ischemia. Regarding the diagnosis, both static and dynamics X-rays, as well as magnetic resonance imaging are important for preoperative evaluation as well as individualizing surgical planning. The choice of the most appropriate technique is affected by patient's clinical condition radiologic findings, as well as surgeon's experience. In opposition to the old belief that patients presenting mild myelopathy should be treated conservatively, there has progressively been amount of evidence indicating that the clinical course of this disease is progressive deterioration and that early surgical intervention improves long-term functional recovery and neurological prognosis. International Scholarly Research Network 2011 2011-09-28 /pmc/articles/PMC3263543/ /pubmed/22389818 http://dx.doi.org/10.5402/2011/463729 Text en Copyright © 2011 Tobias A. Mattei et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Mattei, Tobias A. Goulart, Carlos R. Milano, Jeronimo B. Dutra, Luis Paulo F. Fasset, Daniel R. Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques |
title | Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques |
title_full | Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques |
title_fullStr | Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques |
title_full_unstemmed | Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques |
title_short | Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques |
title_sort | cervical spondylotic myelopathy: pathophysiology, diagnosis, and surgical techniques |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263543/ https://www.ncbi.nlm.nih.gov/pubmed/22389818 http://dx.doi.org/10.5402/2011/463729 |
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