Cargando…

Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques

Cervical spondylotic myelopathy is a degenerative spinal disease which may lead to significant clinical morbidity. The onset of symptoms is usually insidious, with long periods of fixed disability and episodic worsening events. Regarding the pathophysiology of CSM, the repeated injuries to the spina...

Descripción completa

Detalles Bibliográficos
Autores principales: Mattei, Tobias A., Goulart, Carlos R., Milano, Jeronimo B., Dutra, Luis Paulo F., Fasset, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263543/
https://www.ncbi.nlm.nih.gov/pubmed/22389818
http://dx.doi.org/10.5402/2011/463729
_version_ 1782221879671521280
author Mattei, Tobias A.
Goulart, Carlos R.
Milano, Jeronimo B.
Dutra, Luis Paulo F.
Fasset, Daniel R.
author_facet Mattei, Tobias A.
Goulart, Carlos R.
Milano, Jeronimo B.
Dutra, Luis Paulo F.
Fasset, Daniel R.
author_sort Mattei, Tobias A.
collection PubMed
description Cervical spondylotic myelopathy is a degenerative spinal disease which may lead to significant clinical morbidity. The onset of symptoms is usually insidious, with long periods of fixed disability and episodic worsening events. Regarding the pathophysiology of CSM, the repeated injuries to the spinal cord are caused by both static and dynamic mechanical factors. The combination of these factors affects the spinal cord basically through both direct trauma and ischemia. Regarding the diagnosis, both static and dynamics X-rays, as well as magnetic resonance imaging are important for preoperative evaluation as well as individualizing surgical planning. The choice of the most appropriate technique is affected by patient's clinical condition radiologic findings, as well as surgeon's experience. In opposition to the old belief that patients presenting mild myelopathy should be treated conservatively, there has progressively been amount of evidence indicating that the clinical course of this disease is progressive deterioration and that early surgical intervention improves long-term functional recovery and neurological prognosis.
format Online
Article
Text
id pubmed-3263543
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher International Scholarly Research Network
record_format MEDLINE/PubMed
spelling pubmed-32635432012-03-02 Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques Mattei, Tobias A. Goulart, Carlos R. Milano, Jeronimo B. Dutra, Luis Paulo F. Fasset, Daniel R. ISRN Neurol Review Article Cervical spondylotic myelopathy is a degenerative spinal disease which may lead to significant clinical morbidity. The onset of symptoms is usually insidious, with long periods of fixed disability and episodic worsening events. Regarding the pathophysiology of CSM, the repeated injuries to the spinal cord are caused by both static and dynamic mechanical factors. The combination of these factors affects the spinal cord basically through both direct trauma and ischemia. Regarding the diagnosis, both static and dynamics X-rays, as well as magnetic resonance imaging are important for preoperative evaluation as well as individualizing surgical planning. The choice of the most appropriate technique is affected by patient's clinical condition radiologic findings, as well as surgeon's experience. In opposition to the old belief that patients presenting mild myelopathy should be treated conservatively, there has progressively been amount of evidence indicating that the clinical course of this disease is progressive deterioration and that early surgical intervention improves long-term functional recovery and neurological prognosis. International Scholarly Research Network 2011 2011-09-28 /pmc/articles/PMC3263543/ /pubmed/22389818 http://dx.doi.org/10.5402/2011/463729 Text en Copyright © 2011 Tobias A. Mattei et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Mattei, Tobias A.
Goulart, Carlos R.
Milano, Jeronimo B.
Dutra, Luis Paulo F.
Fasset, Daniel R.
Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques
title Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques
title_full Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques
title_fullStr Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques
title_full_unstemmed Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques
title_short Cervical Spondylotic Myelopathy: Pathophysiology, Diagnosis, and Surgical Techniques
title_sort cervical spondylotic myelopathy: pathophysiology, diagnosis, and surgical techniques
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263543/
https://www.ncbi.nlm.nih.gov/pubmed/22389818
http://dx.doi.org/10.5402/2011/463729
work_keys_str_mv AT matteitobiasa cervicalspondyloticmyelopathypathophysiologydiagnosisandsurgicaltechniques
AT goulartcarlosr cervicalspondyloticmyelopathypathophysiologydiagnosisandsurgicaltechniques
AT milanojeronimob cervicalspondyloticmyelopathypathophysiologydiagnosisandsurgicaltechniques
AT dutraluispaulof cervicalspondyloticmyelopathypathophysiologydiagnosisandsurgicaltechniques
AT fassetdanielr cervicalspondyloticmyelopathypathophysiologydiagnosisandsurgicaltechniques