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Serine 129 Phosphorylation of α-Synuclein Cross-Links with Tissue Transglutaminase to Form Lewy Body-Like Inclusion Bodies

Intraneuronal depositions of α-synuclein have been implicated in the pathogenesis of Parkinsons's disease (PD). Previous reports have identified the crosslinking between α-synuclein and tTG (tissue transglutaminase) in both PD patients and the cellular model. However, no researches have been co...

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Detalles Bibliográficos
Autores principales: Bi, Wei, Zhang, GuoHua, Sun, Yuanlin, Zhu, Lihong, Wang, Chuanming, Liang, Yanran, Shi, Qiaoyun, Tao, Enxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263562/
https://www.ncbi.nlm.nih.gov/pubmed/22389828
http://dx.doi.org/10.5402/2011/732879