Promoter Methylation of RASSF1A Associates to Adult Secondary Glioblastomas and Pediatric Glioblastomas

While allelic losses and mutations of tumor suppressor genes implicated in the etiology of astrocytoma have been widely assessed, the role of epigenetics is still a matter of study. We analyzed the frequency of promoter hypermethylation by methylation-specific PCR (MSP) in five tumor suppressor gene...

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Detalles Bibliográficos
Autores principales: Muñoz, Jorge, Inda, María del Mar, Lázcoz, Paula, Zazpe, Idoya, Fan, Xing, Alfaro, Jorge, Tuñón, Teresa, Rey, Juan A., Castresana, Javier S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263565/
https://www.ncbi.nlm.nih.gov/pubmed/22389839
http://dx.doi.org/10.5402/2012/576578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263565/
https://www.ncbi.nlm.nih.gov/pubmed/22389839
http://dx.doi.org/10.5402/2012/576578

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