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Development of an Oral Form of Azacytidine: 2′3′5′Triacetyl-5-Azacytidine
Myelodysplastic syndromes (MDSs) represent a group of incurable stem-cell malignancies which are predominantly treated by supportive care. Epigenetic silencing through promoter methylation of a number of genes is present in poor-risk subtypes of MDS and often predicts transformation to acute myeloge...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263612/ https://www.ncbi.nlm.nih.gov/pubmed/22295208 http://dx.doi.org/10.1155/2011/965826 |