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Hyperplastic Polyps Are Innocuous Lesions in Hereditary Nonpolyposis Colorectal Cancers

Aims. To compare methylation profiles, protein expression, and microsatellite instability (MSI) of sporadic, HNPCC, and familial hyperplastic polyps (HPs). Methods. Methylation-specific PCR (MSP) and pyrosequencing assessed p16, MGMT, hMLH-1, MINT 1, and MINT 31 methylation. IHC (Immunohistochemistr...

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Detalles Bibliográficos
Autores principales:	Speake, D., O'Sullivan, J., Evans, D. G., Lalloo, F., Hill, J., McMahon, R. F. T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263654/ https://www.ncbi.nlm.nih.gov/pubmed/22312515 http://dx.doi.org/10.1155/2011/653163

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