Folic Acid Supplementation for Women of Childbearing Age versus Supplementation for the General Population: A Review of the Known Advantages and Risks

This paper focuses on the current best-evidence-based clinical practices and controversies surrounding folic acid supplementation/fortification for the prevention of neural tube defects (NTDs) during early pregnancy. The paper also discusses the controversies surrounding the effect of folic acid on...

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Detalles Bibliográficos
Autores principales: Shelke, Nikhil, Keith, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263835/
https://www.ncbi.nlm.nih.gov/pubmed/22295182
http://dx.doi.org/10.1155/2011/173705
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author Shelke, Nikhil
Keith, Louis
author_facet Shelke, Nikhil
Keith, Louis
author_sort Shelke, Nikhil
collection PubMed
description This paper focuses on the current best-evidence-based clinical practices and controversies surrounding folic acid supplementation/fortification for the prevention of neural tube defects (NTDs) during early pregnancy. The paper also discusses the controversies surrounding the effect of folic acid on the prevention as well as the promotion of cancer. Sufficient data is available to safely conclude that folic acid reduces the risk of NTDs during pregnancy; however, a safe dosage has not yet been calculated for the rest of the population. More research is necessary to study the complete role of folic acid in human growth and development.
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spelling pubmed-32638352012-01-31 Folic Acid Supplementation for Women of Childbearing Age versus Supplementation for the General Population: A Review of the Known Advantages and Risks Shelke, Nikhil Keith, Louis Int J Family Med Review Article This paper focuses on the current best-evidence-based clinical practices and controversies surrounding folic acid supplementation/fortification for the prevention of neural tube defects (NTDs) during early pregnancy. The paper also discusses the controversies surrounding the effect of folic acid on the prevention as well as the promotion of cancer. Sufficient data is available to safely conclude that folic acid reduces the risk of NTDs during pregnancy; however, a safe dosage has not yet been calculated for the rest of the population. More research is necessary to study the complete role of folic acid in human growth and development. Hindawi Publishing Corporation 2011 2011-05-23 /pmc/articles/PMC3263835/ /pubmed/22295182 http://dx.doi.org/10.1155/2011/173705 Text en Copyright © 2011 N. Shelke and L. Keith. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Shelke, Nikhil
Keith, Louis
Folic Acid Supplementation for Women of Childbearing Age versus Supplementation for the General Population: A Review of the Known Advantages and Risks
title Folic Acid Supplementation for Women of Childbearing Age versus Supplementation for the General Population: A Review of the Known Advantages and Risks
title_full Folic Acid Supplementation for Women of Childbearing Age versus Supplementation for the General Population: A Review of the Known Advantages and Risks
title_fullStr Folic Acid Supplementation for Women of Childbearing Age versus Supplementation for the General Population: A Review of the Known Advantages and Risks
title_full_unstemmed Folic Acid Supplementation for Women of Childbearing Age versus Supplementation for the General Population: A Review of the Known Advantages and Risks
title_short Folic Acid Supplementation for Women of Childbearing Age versus Supplementation for the General Population: A Review of the Known Advantages and Risks
title_sort folic acid supplementation for women of childbearing age versus supplementation for the general population: a review of the known advantages and risks
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263835/
https://www.ncbi.nlm.nih.gov/pubmed/22295182
http://dx.doi.org/10.1155/2011/173705
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