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Fluorescent Silicate Materials for the Detection of Paraoxon

Porphyrins are a family of highly conjugated molecules that strongly absorb visible light and fluoresce intensely. These molecules are sensitive to changes in their immediate environment and have been widely described for optical detection applications. Surfactant-templated organosilicate materials...

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Autores principales: Johnson, Brandy J., Melde, Brian J., Thomas, Cassandra, Malanoski, Anthony P., Leska, Iwona A., Charles, Paul T., Parrish, Damon A., Deschamps, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264481/
https://www.ncbi.nlm.nih.gov/pubmed/22294928
http://dx.doi.org/10.3390/s100302315
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author Johnson, Brandy J.
Melde, Brian J.
Thomas, Cassandra
Malanoski, Anthony P.
Leska, Iwona A.
Charles, Paul T.
Parrish, Damon A.
Deschamps, Jeffrey R.
author_facet Johnson, Brandy J.
Melde, Brian J.
Thomas, Cassandra
Malanoski, Anthony P.
Leska, Iwona A.
Charles, Paul T.
Parrish, Damon A.
Deschamps, Jeffrey R.
author_sort Johnson, Brandy J.
collection PubMed
description Porphyrins are a family of highly conjugated molecules that strongly absorb visible light and fluoresce intensely. These molecules are sensitive to changes in their immediate environment and have been widely described for optical detection applications. Surfactant-templated organosilicate materials have been described for the semi-selective adsorption of small molecule contaminants. These structures offer high surface areas and large pore volumes within an organized framework. The organic bridging groups in the materials can be altered to provide varied binding characteristics. This effort seeks to utilize the tunable binding selectivity, high surface area, and low materials density of these highly ordered pore networks and to combine them with the unique spectrophotometric properties of porphyrins. In the porphyrin-embedded materials (PEMs), the organosilicate scaffold stabilizes the porphyrin and facilitates optimal orientation of porphyrin and target. The materials can be stored under ambient conditions and offer exceptional shelf-life. Here, we report on the design of PEMs with specificity for organophosphates and compounds of similar structure.
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spelling pubmed-32644812012-01-31 Fluorescent Silicate Materials for the Detection of Paraoxon Johnson, Brandy J. Melde, Brian J. Thomas, Cassandra Malanoski, Anthony P. Leska, Iwona A. Charles, Paul T. Parrish, Damon A. Deschamps, Jeffrey R. Sensors (Basel) Article Porphyrins are a family of highly conjugated molecules that strongly absorb visible light and fluoresce intensely. These molecules are sensitive to changes in their immediate environment and have been widely described for optical detection applications. Surfactant-templated organosilicate materials have been described for the semi-selective adsorption of small molecule contaminants. These structures offer high surface areas and large pore volumes within an organized framework. The organic bridging groups in the materials can be altered to provide varied binding characteristics. This effort seeks to utilize the tunable binding selectivity, high surface area, and low materials density of these highly ordered pore networks and to combine them with the unique spectrophotometric properties of porphyrins. In the porphyrin-embedded materials (PEMs), the organosilicate scaffold stabilizes the porphyrin and facilitates optimal orientation of porphyrin and target. The materials can be stored under ambient conditions and offer exceptional shelf-life. Here, we report on the design of PEMs with specificity for organophosphates and compounds of similar structure. Molecular Diversity Preservation International (MDPI) 2010-03-19 /pmc/articles/PMC3264481/ /pubmed/22294928 http://dx.doi.org/10.3390/s100302315 Text en © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Johnson, Brandy J.
Melde, Brian J.
Thomas, Cassandra
Malanoski, Anthony P.
Leska, Iwona A.
Charles, Paul T.
Parrish, Damon A.
Deschamps, Jeffrey R.
Fluorescent Silicate Materials for the Detection of Paraoxon
title Fluorescent Silicate Materials for the Detection of Paraoxon
title_full Fluorescent Silicate Materials for the Detection of Paraoxon
title_fullStr Fluorescent Silicate Materials for the Detection of Paraoxon
title_full_unstemmed Fluorescent Silicate Materials for the Detection of Paraoxon
title_short Fluorescent Silicate Materials for the Detection of Paraoxon
title_sort fluorescent silicate materials for the detection of paraoxon
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264481/
https://www.ncbi.nlm.nih.gov/pubmed/22294928
http://dx.doi.org/10.3390/s100302315
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