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Effects of BRCA2 deficiency on telomere recombination in non-ALT and ALT cells
BACKGROUND: Recent studies suggest that BRCA2 affects telomere maintenance. Interestingly, anti cancer treatments that involve BRCA2 and telomerase individually are currently being explored. In the light of the above recent studies their combinatorial targeting may be justified in the development of...
Autores principales: | Sapir, Ester, Gozaly-Chianea, Yaghoub, Al-Wahiby, Suliman, Ravindran, Sainu, Yasaei, Hemad, Slijepcevic, Predrag |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264516/ https://www.ncbi.nlm.nih.gov/pubmed/22152194 http://dx.doi.org/10.1186/2041-9414-2-9 |
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